Modafinil vs Armodafinil – compare two medications

A quick comparision: modafinil vs armodafinil

Modafinil vs armodafinil are two popular narcolepsy and ADHD medications. We compare several factors includng cost, duration, effectiveness and how fast they work. Find out which drug is the most effective sleep disorder treatment for you.

Armodafinil vs Modafinil – What is modafinil?

Modafinil is the medical name for the drug Provigil, which was initially created for sleep-related diseases like narcolepsy and other diseases which cause excessive daytime sleepiness. Modafinil has a half life of about 12 hours and it is taken up to twice in one day. It increases cognitive function leading to increased levels of alertness.

Modafinil vs Armodafinil – What is armodafinil?

Armodafinil is the newest drug on the market for treating excessive daytime sleepines, and it is the same substance as TEVA Concerta which is used for treating ADHD. It is seen as the new and improved version of modafinil, and while the positive effects are mostly the same, it is a more purified form of modafinil leading to fewer negative side-effects.

Artvigil is the most popular form of generic Armodafinil, because of potency matched with extremely low price, nootropic lovers everywhere choose Artvigil as their preferred type of armodafinil. It is manufactured in India by HAB Pharmaceuticals in their quality-controlled pristine labratories. Because Artvigil is a generic version of nuvgil prices are around $49 for 20 pills. This is MANY times cheaper than the market price of Nuvigil. Artvigil comes in pills of 150mg vaccum sealed inside ultra-modern packaging.

Waklert is an incredibly popular form of generic modafinil manufactured in india by SUN pharmaceuticals. There is virtually no difference between Waklert and Artvigil except the binders/excipients used to make the pills. Another difference is that Waklert is $10 more expensive. Despite this small increase in price over Artvigil, waklert is often the preferred choice for people who do not take kindly to some kinds of pill-binder-agents which contain lactose. Waklert is still many times cheaper than brand Nuvigil, at 59$ for 20 pills.

Nuvigil is the branded version of Armodafinil which is manufactured by Cephalon INC in the United States, it is superceeded by generic versions of the drug: Waklert & Artvigil as they have the exact same wakeful-promoting effects for many times cheaper. The cost for Nuvigil oral tablet 50 mg is around $241 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Nuvigil is available, see armodafinil prices for Artvigil and Waklert.

How does modafinil and armodafinil work?

Armodafinil, like modafinil, is what is known as a wakefulness promoting agent (or eugeroic) which when taken will increase levels of mental alertness and as a result symptoms of sleep deprivation are treated.  Modafinil and armodafinil change the amounts of various neuro-chemicals in the brain, in particular inhibiting the absorbtion of dopamine from synapses. This leads to an increase of mental arousal and motivation allowing the patient to become more physically and mentally active.

These individual drugs are primarily used to treat the symptoms of the disease Narcolepsy. When either modafinil or armodafinil are taken the excessive daytime sleepiness associated with Narcolepsy is significantly diminished. In effect then, modafinil and armodafinil are stimulants. Modafinil was first called Provigil and Armodafinil was first called Nuvigil – these drugs have been available for purchase for over 17+ years now and because they increase focus, motivation and energy-levels these supplements are used by healthy people for the purpose of cognitive enhancement.

Is Armodafinil stronger than Modafinil?

Armodafinil is the new and improved version of modafinil. While many people think that Armodafinil was created so that big pharma can prolong drug patent technology, it is clear to physicians that armodafinil is infact a less chemically complex compound, as it is a more refined version of modafinil. Armodafinil generally has fewer side-effects as the elimination profile of the drug is much smoother. Patients review their experience as “cleaner” and “stronger”.

Does armodafinil have fewer side effects?

Why Armodafinil is smoother?

Firstly, modafinil is a compound composed of two distinct chemicals:



R-Modafinil. It is only R-modafinil isomer which has the stimulating effects. Armodafinil (or R-Modafinil) only contains the R-Modafinil variant. This makes the drug cleaner, smoother and simpler. There are indeed fewer side effects for mainly two reasons:

S-Modafinil has side-effects of its own, now with this isomer eliminated, there are fewer overall side-effects.

S-Modafinil while inactive does comepte for binding sites with R-Modafinil, basically preventing some if not all of the compund from taking effect. This means that higher doses of modafinil are required in comparision to armodafinil. Modafinil comes in doses of 200mg and armodafinil in doses of 150mg, with less of the active ingredient required inside the body, this means lower amounts of armodafinil will need to be taken. The less you take of a drug, the fewer the negative effects.

Armodafinil contains only one enantiomer–R-modafinil–and is therefore said to be “enantiopure” (containing only a single enantiomer).

Is Armodafinil legal?

As Armodafinil is prescribed to treat sleep-related diseases, in the US it is regulated by the FDA and in the UK it is a Precription Only Medicine, meaning that in both the US and UK you need a valid prescription in order to purchase modafinil medicine. Despite armodafinils status as a medicine, there are swarms of healthy individuals using the drug for cognitive enhancement. In particular a lot of students are using the drug for focus during study. This off-label usage of armodafinil tablets has led to many asking if it is legal to purchase.

The facts

The aspect of modafinil vs armodafinil invoke legal considerations – while it is illegal to buy modafinil (provigil) online prescription-only drugs without a consultation or prescription in the UK, the law does not currently apply to websites abroad if you are buying for personal use – see here for the United Kingdom

For customers in the United States the law is a bit murky, while a prescription is technically and strictly necessary, still many people are importing drugs without a problem. The FDA advises to not import more than a 3 month supply of the drug.

What are the risks?

Unless you are importing extraordinarily large quantities (1000 pills) then the worst that can happen, from information gained from reviews, is: that simply your package will not make it through customs and it will get seized. In the US when this happens you will get a “love letter” from US customs informing you of the seizure, however it stops there with no further follow-up.

Most online vendors of Armodafinil are very aware of this fact in stating that around 3% of their total shipments get seized, this is why online pharmacies advertise a refund or free re-shipment of any seized orders.